发明名称 |
Uses of IL-12 in hematopoiesis |
摘要 |
Methods for enhancing or stimulating hematopoiesis including the step of administering Interleukin-12 (IL-12) to yield hematopoietic recovery in a mammal in need. Preferred methods include the step of administering IL-12 as an adjuvant therapy to alleviate the hematopoietic toxicities associated with one or more treatment regimens used to combat a disease state. Other methods include administering IL-12 to ameliorate various hematopoietic deficiencies. Still other methods are directed to uses of IL-12 for in-vivo proliferation of hematopoietic repopulating cells, hematopoietic progenitor cells and hematopoietic stem cells. Other disclosed methods are directed to uses of Il-12 for bone marrow preservation or recovery.
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申请公布号 |
US7939058(B2) |
申请公布日期 |
2011.05.10 |
申请号 |
US20040886267 |
申请日期 |
2004.07.06 |
申请人 |
UNIVERSITY OF SOUTHERN CALIFORNIA |
发明人 |
CHEN TINGCHAO;ZHAO YI;ANDERSON W. FRENCH |
分类号 |
A61K38/19;A61K38/20;A61K45/00;A61N5/00;C07K14/52 |
主分类号 |
A61K38/19 |
代理机构 |
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地址 |
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