| 摘要 |
FIELD: chemistry. ^ SUBSTANCE: in the compound of formula I, M denotes identical or different metal atoms selected from a group comprising: Pd, Fe, Mn, Co, Ni, Cu, Zn or Mo, R1 and R2 independently denote hydrogen, amino, hydroxyl, carboxy, cyano, C1-12alkyl, C2-12alkenyl, C2-12alkynyl, C1-12alkoxy, C1-12alkylamino, C1-12alkoxycarbonyl, C1-12alkylamido,arylamido. Alkyl groups in the said substitutes may in turn be substituted with one or more of the following groups: hydroxyl, oxo, carboxy, amino or amido, R3-R10 independently denote hydrogen, or NHR3R4 and NHR5R6, taken together, and(or) NHR7R8 and NHR9R10, taken together, denote a ligand (or ligands) containing one or more donor aliphatic or aromatic nitrogen atoms and which occupy the cis-position near metal (M) atoms. The invention also discloses a pharmaceutical composition, use of the compound to prepare a medicinal drug and a therapeutic treatment method. ^ EFFECT: obtaining compounds capable of boosting efficiency of medicinal drugs. ^ 25 cl, 17 ex, 23 tbl |
