发明名称 |
Anti-EGFR antibodies with an improved anti-tumor activity and compositions and articles of manufacture comprising same |
摘要 |
A method of identifying a combination of antibodies with a combined improved anti tumor activity is provided. The method comprising identifying at least two anti RTK antibodies capable of inducing synergistic endocytosis of the RTK in a cell expressing the RTK, thereby identifying the combination of antibodies with the combined improved anti-tumor activity.
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申请公布号 |
US7939072(B2) |
申请公布日期 |
2011.05.10 |
申请号 |
US20090320207 |
申请日期 |
2009.01.21 |
申请人 |
YEDA RESEARCH AND DEVELOPMENT CO. LTD. |
发明人 |
YARDEN YOSEF;SELA MICHAEL |
分类号 |
A61K39/395 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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