| 发明名称 |
RNA DETECTION ASSAYS |
| 摘要 |
The present invention provides novel cleavage agents and polymerases for the cleavage and modification of nucleic acid. The cleavage agents and polymerases find use, for example, for the detection and characterization of nucleic acid sequences and variations in nucleic acid sequences. In some embodiments, the 5′ nuclease activity of a variety of enzymes is used to cleave a target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.
|
| 申请公布号 |
US2011104682(A1) |
申请公布日期 |
2011.05.05 |
| 申请号 |
US20100898490 |
申请日期 |
2010.10.05 |
| 申请人 |
THIRD WAVE TECHNOLOGIES, INC. |
发明人 |
ALLAWI HATIM;ARGUE BRAD T.;BARTHOLOMAY CHRISTIAN TOR;CHEHAK LUANNE;CURTIS MICHELLE L.;EIS PEGGY S.;HALL JEFF G.;IP HON S.;JI LIN;KAISER MICHAEL;KWIATKOWSKI, JR. ROBERT W.;LUKOWIAK ANDREW A.;LYAMICHEV VICTOR;LYAMICHEVA NATALIE E.;MA WUPO;NERI BRUCE P.;OLSON SARAH M.;OLSON-MUNOZ MARILYN C.;SCHAEFER JAMES J.;SKRZYPCZYNSKI ZBIGNIEV;TAKOVA TSETSKA Y.;THOMPSON LISA C.;VEDVIK KEVIN L. |
| 分类号 |
C12Q1/68;C12N9/12;C12N9/14;C12N9/22;C12N15/55 |
主分类号 |
C12Q1/68 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
