发明名称 |
PAI-1 EXPRESSION AND ACTIVITY INHIBITORS FOR THE TREATMENT OF OCULAR DISORDERS |
摘要 |
The invention concerns in one embodiment a method for treating glaucoma or elevated IOP in a patient comprising administering to the patient an effective amount of a composition comprising an agent that inhibits PAI-1 expression or PAI-1 activity. Another embodiment of the present invention is a method of treating a PAI-1-associated ocular disorder in a subject in need, comprising administering to the patient an effective amount of a composition comprising an agent that inhibits PAI-1 activity or expression.
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申请公布号 |
US2011105574(A1) |
申请公布日期 |
2011.05.05 |
申请号 |
US201113006984 |
申请日期 |
2011.01.14 |
申请人 |
ALCON RESEARCH, LTD. |
发明人 |
FLEENOR DEBRA L.;SHEPARD ALLAN R.;PANG IOK-HOU;HELLBERG MARK R.;CLARK ABBOT F. |
分类号 |
A61K31/41;A61K31/403;A61P27/02 |
主分类号 |
A61K31/41 |
代理机构 |
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