发明名称 Diaminoalkane aspartic protease inhibitors
摘要 Diaminoalkanes of Formula I have now been found which are orally active and bind to aspartic proteases to inhibit their activity. They are useful in the treatment or amelioration of diseases associated with elevated levels of aspartic protease activity. The invention also relates to a method for the use of the compounds of Formula I in ameliorating or treating aspartic protease related disorders in a subject in need thereof comprising administering to said subject an effective amount of a compound of Formula I.
申请公布号 US2011105506(A1) 申请公布日期 2011.05.05
申请号 US20100802142 申请日期 2010.05.28
申请人 VITAE PHARMACEUTICALS, INC. 发明人 BALDWIN JOHN J.;CLAREMON DAVID A.;TICE COLIN M.;CACATIAN SALVACION;DILLARD LAWRENCE W.;ISHCHENKO ALEXEY V.;YUAN JING;XU ZHENRONG;MCGEEHAN GERARD;ZHAO WEI;SIMPSON ROBERT D.;SINGH SURESH B.;FLAHERTY PATRICK T.;WERY JEAN-PIERRE
分类号 A61K31/5375;A61K31/445;A61K31/451;A61K31/4525;A61K31/454;C07D211/22;C07D211/60;C07D265/30;C07D405/10;C07D417/04 主分类号 A61K31/5375
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