发明名称 |
PROCESS FOR PREPARING FONDAPARINUX SODIUM AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF |
摘要 |
Processes for the synthesis of the Factor Xa anticoagulent Fondaparinux, and related compounds are described. Also described are protected pentasaccharide intermediates as well as efficient and scalable processes for the industrial scale production of Fondaparinux sodium by conversion of the protected pentasaccharide intermediates via a sequence of deprotection and sulfonation reactions.
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申请公布号 |
US2011105418(A1) |
申请公布日期 |
2011.05.05 |
申请号 |
US20100847719 |
申请日期 |
2010.07.30 |
申请人 |
RELIABLE BIOPHARMACEUTICAL CORPORATION |
发明人 |
NADJI SOURENA;SMOOT JAMES T.;VANARTSDALEN JOSEPH A. |
分类号 |
A61K31/7028;A61K31/7048;A61P7/02;C07H15/04;C07H17/04 |
主分类号 |
A61K31/7028 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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