发明名称 |
Female Reproductive Tract and Anal Prophylaxes |
摘要 |
The present invention provides methods for boosting mucosal immunity in the female reproductive tract of pre- and post-menopausal women using a TGF-beta inhibitor, a Selective Estrogen Receptor Modulator, and/or a recombinant commensal bacterium that expresses endogenous microbicides into the intestinal tract or reproductive tract of a subject. It also provides methods for boosting innate and adaptive immunity by providing a glucocorticoid. Methods for preventing sexually transmitted infections including HIV infection are also provided.
|
申请公布号 |
US2011104121(A1) |
申请公布日期 |
2011.05.05 |
申请号 |
US20090993349 |
申请日期 |
2009.05.21 |
申请人 |
WIRA CHARLES R;FAHEY JOHN V;SENTMAN CHARLES L;GUYRE PAUL M |
发明人 |
WIRA CHARLES R.;FAHEY JOHN V.;SENTMAN CHARLES L.;GUYRE PAUL M. |
分类号 |
A61K35/74;A61K31/138;A61K31/40;A61K31/4439;A61K31/4535;A61K31/4709;A61K31/519;A61K31/525;A61K31/55;A61K31/573;A61P31/18;C12N5/00 |
主分类号 |
A61K35/74 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|