发明名称 |
TRIS-QUARTERNARY AMMONIUM SALTS AND METHODS FOR MODULATING NEURONAL NICOTINIC ACETYLCHOLINE RECEPTORS |
摘要 |
Provided are tris-quaternary ammonium compounds which are modulators of nicotinic acetylocholine receptors. Also provided are methods of using the compounds for modulating the function of a nicotinic acetylcholine receptor, and for the prevention and/or treatment of central nervous system disorders, substance use and/or abuse and or gastrointestinal tract disorders. |
申请公布号 |
US2011105556(A1) |
申请公布日期 |
2011.05.05 |
申请号 |
US20060158192 |
申请日期 |
2006.12.22 |
申请人 |
UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION |
发明人 |
CROOKS PETER A.;DWOSKIN LINDA P.;PAPKE ROGER;ZHENG GUANGRONG;SUMITHRAN SANGEETHA |
分类号 |
A61K31/4725;A61K31/444;A61K31/47;A61P1/00;A61P1/04;A61P1/10;A61P1/12;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P25/30;C07D401/14 |
主分类号 |
A61K31/4725 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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