NO-DONATING CORDICOSTEROID WITH IMPROVED PHARMACOKINETIC, ANTI-INFLAMMATORY AND VASODILATORY PROPERTIES

摘要

The present invention involves the use of a steroid linked to nitric oxide (preferred steroid is budesonide) for treating respirator}' diseases by decreasing neutrophil sputum levels and decreasing plasma CRP levels Respiratory diseases treated include asthma, COPD (chronic obstructive pulmonary disorder), eosinophilic cough, bronchitis, sarcoidosis, pulmonary fibrosis, rhinitis, pulmonary hypertension, cystic fibrosis, bronchiectasis and sinusitis