发明名称 |
PEPTIDE COMPOSITIONS AND METHODS FOR INHIBITING HERPESVIRUS INFECTION |
摘要 |
The present invention provides an isolated peptide having an amino acid residue sequence that comprises at least one human cytomegalovirus glycoprotein B (HCMV-gB) sequence segment, each HCMV-gB sequence segment consisting of at least 8 and not more than 60 consecutive amino acid residues from residues 146 to 315, residues 476 to 494 of SEQ ID NO: 1, or from a sequence variant of residues 146 to 315 or 476 to 494 of SEQ ID NO: 1 that has at least 70 % sequence identity thereto. The peptides of the invention are useful for treating, preventing, or inhibiting a herpesvirus (e.g., Herpes Simplex Virus- 1, Human Cytomegalovirus, and the like) infection in a subject. |
申请公布号 |
WO2011053798(A2) |
申请公布日期 |
2011.05.05 |
申请号 |
WO2010US54743 |
申请日期 |
2010.10.29 |
申请人 |
THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND;MELNIK, LILIA I.;GARRY, ROBERT F.;MORRIS, CINDY A. |
发明人 |
MELNIK, LILIA I.;GARRY, ROBERT F.;MORRIS, CINDY A. |
分类号 |
C07K14/045;A61K39/245;A61P31/22 |
主分类号 |
C07K14/045 |
代理机构 |
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地址 |
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