| 发明名称 |
POLYMERIC SYSTEMS CONTAINING INTRACELLULAR RELEASABLE DISULFIDE LINKER FOR THE DELIVERY OF OLIGONUCLEOTIDES |
| 摘要 |
The present invention provides polymeric prodrugs including an intracellular releasable disulfide linker for the delivery of oligonucleotides. Methods of making the compounds as well as methods of delivering nucleic acids to tumor cells in a mammal using the same are also provided.
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| 申请公布号 |
US2011105413(A1) |
申请公布日期 |
2011.05.05 |
| 申请号 |
US20090994266 |
申请日期 |
2009.05.22 |
| 申请人 |
ENZON PHARMACEUTICALS, INC. |
发明人 |
ZHAO HONG;REDDY PRASANNA |
| 分类号 |
A61K38/02;A61K31/7088;A61K31/713;A61P35/00;C08B37/00;C12N5/071;C12N5/09 |
主分类号 |
A61K38/02 |
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