发明名称 |
Oncotherapeutic Application of Inhibitors of High-Affinity Glucose Transporters |
摘要 |
The subject invention concerns materials and methods for treating oncological disorders in a person or animal using any agent or compound that inhibits uptake of glucose into a cell. The subject invention also concerns methods for inducing apoptosis and inhibiting the proliferation or survival of a cell. In one embodiment, the methods comprise administering an effective amount of an agent or compound that inhibits the activity of one or more glucose transporter proteins, such as Glut-1. An antibody that binds to and inhibits a glucose transporter protein can be used in the present methods. |
申请公布号 |
US2011104249(A1) |
申请公布日期 |
2011.05.05 |
申请号 |
US20080673677 |
申请日期 |
2008.08.15 |
申请人 |
UNIVERSITY OF SOUTH FLORIDA |
发明人 |
SIMON GEORGE R. |
分类号 |
A61K9/127;A61K31/17;A61K31/196;A61K31/282;A61K31/337;A61K31/351;A61K31/4188;A61K31/437;A61K31/475;A61K31/505;A61K31/506;A61K31/513;A61K31/517;A61K31/519;A61K31/522;A61K31/5377;A61K31/66;A61K31/675;A61K31/69;A61K31/704;A61K31/7048;A61K31/7068;A61K31/7105;A61K31/711;A61K33/24;A61K38/14;A61K38/50;A61K39/395;A61K101/02;A61P35/00;C12N5/071 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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