Transcutaneous immunostimulation

摘要

Disclosed is an adjuvant for transcutaneous immunostimulation comprising:
(a) providing a subject in need of immunization with a vaccine,
(b) applying at least one adjuvant epicutaneously to the subject's skin, and
(c) immunizing the subject with the vaccine by a route of administration other than transcutaneous, wherein the vaccine comprises one or more antigens;
whereby the at least one adjuvant causes transcutaneous immunostimulation by inducing an immune response specific for the one or more antigens, wherein the immune response stimulated by the at least one adjuvant is more effective than in the absence of the at least one adjuvant.