| 发明名称 |
LIPID DERIVATIVES OF AMINOGLYCOSIDES |
| 摘要 |
The invention concerns novel transfecting compounds consisting of an aminoglycoside bound to a lipid via a spacer, and their polyguanidyl derivatives. Said compounds are useful for in vitro, ex vivo or in vivo transfection of nucleic acids in different cell types.
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| 申请公布号 |
CA2458626(C) |
申请公布日期 |
2011.05.03 |
| 申请号 |
CA20022458626 |
申请日期 |
2002.08.29 |
| 申请人 |
AVENTIS PHARMA S.A.;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE |
发明人 |
LEHN, JEAN-MARIE;LEHN, PIERRE;VIGNERON, JEAN-PIERRE |
| 分类号 |
A61K47/10;C07J41/00;A61K9/127;A61K31/575;A61K31/7088;A61K31/711;A61K47/24;A61K47/26;A61K47/34;A61K47/42;A61K47/44;A61K48/00 |
主分类号 |
A61K47/10 |
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