| 摘要 |
Disclosed is a compound having the formula I-A or a pharmaceutically acceptable salt, hydrate or solvate of such compound wherein R1 represents O-C1-6alkyl, O-C2-6alkynyl, O-C2-6alkenyl, O-C3-7cycloalkyl or O-alkylcycloalkyl; or R1 and R2 form a heterocycle; and wherein the rest of the substituents are disclosed within the specification. Also disclosed is the use of the compound of formula I for preparing a tracer for imaging FSH receptors and for manufacturing a medicament for the treatment or prevention of a condition wichin is affected by the FSH receptor negative allosteric modulators such as uterine fibroids, endometriosis, polycystic ovarian disease, dysfunctional uterine bleeding, hormone-dependent cancer, prostate cancer, uterine cancer, breast cancer and ovarian cancer and osteoporosis, and for contraception.
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