发明名称 METHOD OF PREPARING A LATANOPROST OPHTHALMIC SOLUTION AND THE RESULTING SOLUTION
摘要 A method of solubilizing an analog active agent of the prostaglandin F2α, such as latanoprost, is described and a method of preparing an ophthalmic solution of the solubilized latanoprost for the treatment of distinct ocular ailments. This invention also refers to an ophthalmic aqueous solution resulting from the aforementioned method, which is characterized by its chemical stability at room temperature, its safety, and innocuousness and efficiency in the treatment of the patient. The new ophthalmic aqueous solution is distinguished because its pharmaceutical value is found in the handling of a vehicle of easy access that not only permits the solubility of latanoprost, but also promotes its chemical stability and, a greater tolerance of the patient with its ophthalmic application for the treatment of the patient's ailment.
申请公布号 US2011098354(A1) 申请公布日期 2011.04.28
申请号 US20110983721 申请日期 2011.01.03
申请人 JIMENEZ-BAYARDO ARTURO;TORNERO-MONTANO JOSE RUBEN;LOPEZ-SANCHEZ MARIA ISABEL;CRUZ-OLMOS ENRIQUE 发明人 JIMENEZ-BAYARDO ARTURO;TORNERO-MONTANO JOSE RUBEN;LOPEZ-SANCHEZ MARIA ISABEL;CRUZ-OLMOS ENRIQUE
分类号 A61K31/215;A61K31/5575;A61P27/02 主分类号 A61K31/215
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