| 发明名称 |
Gem-Disubstituted and Spirocyclic Amino Pyridines/Pyrimidines as Cell Cycle Inhibitors |
| 摘要 |
Compounds, pharmaceutical compositions and methods are provided that are useful in the treatment of CDK4-me-dialed disorders, such as cancer. The subject compounds arc gem-disubstituted or spimcyclic pyridine, pyrimidine and triazine derivatives.
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| 申请公布号 |
US2011097305(A1) |
申请公布日期 |
2011.04.28 |
| 申请号 |
US20090936725 |
申请日期 |
2009.04.06 |
| 申请人 |
AMGEN INC. |
发明人 |
CONNORS RICHARD V.;DAI KANG;EKSTEROWICZ JOHN;FAN PINGCHEN;FISHER BENJAMIN;FU JIASHENG;LI KEXUE;LI ZHIHONG;MCGEE LAWRENCE R.;SHARMA RAJIV;WANG XIAODONG |
| 分类号 |
A61K38/21;A61K31/527;A61K31/5377;A61P31/00;A61P35/00;A61P35/04;A61P37/02;C07D403/12;C07D471/10;C07D491/052;C07D491/147 |
主分类号 |
A61K38/21 |
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