发明名称 |
METHODS AND COMPOSITIONS FOR DIAGNOSIS AND TREATMENT OF GENETIC AND RETINAL DISEASE |
摘要 |
A process of detecting the presence of or susceptibility to a disease involving the Frizzled-4 receptor is provided. The inventive method determines the presence or absence of one or more mutations in Frizzled-4 alone or in conjunction with other proteins such as Norrin and LRP5. The presence of a mutation predicts the presence of a disease or susceptibility to a disease. The inventive process further provides correction or prevention of a disease by administration of frizzled-4 to a subject to alter or maintain a physiological function. |
申请公布号 |
WO2011050096(A2) |
申请公布日期 |
2011.04.28 |
申请号 |
WO2010US53422 |
申请日期 |
2010.10.20 |
申请人 |
RETINAL SOLUTIONS LLC;DRENSER, KIMBERLY |
发明人 |
DRENSER, KIMBERLY |
分类号 |
C12Q1/68;C12N15/09;G01N33/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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