| 发明名称 |
COMPOSITIONS FOR TREATMENT OF CYSTIC FIBROSIS AND OTHER CHRONIC DISEASES |
| 摘要 |
The present invention relates to pharmaceutical compositions comprising an inhibitor of epithelial sodium channel activity in combination with at least one compound of Formula I, Formula II, or Formula III. The invention also relates to solid forms and to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis using the pharmaceutical combination compositions. |
| 申请公布号 |
WO2011050325(A1) |
申请公布日期 |
2011.04.28 |
| 申请号 |
WO2010US53852 |
申请日期 |
2010.10.22 |
| 申请人 |
VERTEX PHARMACEUTICALS INCORPORATED;VAN GOOR, FREDRICK, F.;BURTON, WILLIAM, LAWRENCE |
发明人 |
VAN GOOR, FREDRICK, F.;BURTON, WILLIAM, LAWRENCE |
| 分类号 |
A61K31/404;A61K31/443;A61K31/4965;A61K31/501;A61K45/06;A61P11/00;A61P19/10;A61P43/00 |
主分类号 |
A61K31/404 |
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