发明名称 FLUORESCENT NEAR INFRA-RED (NIR) DYES
摘要 A compound of formula (I) is described in which each A, which may be the same or different, is a halide selected from fluoride, chloride, bromide and iodide, or is O-Y, wherein Y is a substituted or unsubstituted, saturated or unsaturated, straight or branched chain alkyl moiety. R1, R2, R3, R6, R7, and R8 are each independently H, OH, NO2 or O-L-X, wherein L is a spacer group, and X is a conjugation group or a water- solubilizing group. At least one of R1, R2, R3 is OH or O-L-X and at least one of R6, R7, and R8 is OH or O-L-X. R4 and R5, which may be the same or different, are each independently H; or are a substituted or unsubstituted, saturated or unsaturated, cyclic moiety; a substituted or unsubstituted, saturated or unsaturated heterocyclic moiety; or a substituted or unsubstituted, saturated or unsaturated, straight or branched chain alkyl moiety. Also described are dye conjugates comprising a compound of the invention.
申请公布号 WO2011048217(A1) 申请公布日期 2011.04.28
申请号 WO2010EP65991 申请日期 2010.10.22
申请人 HAE THERAPEUTICS;O'SHEA, DONAL 发明人 O'SHEA, DONAL
分类号 C07F5/02 主分类号 C07F5/02
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