发明名称 |
MGLUR4 ALLOSTERIC POTENTIATORS, COMPOSITIONS, AND METHODS OF TREATING NEUROLOGICAL DYSFUNCTION |
摘要 |
<p>Pyrrole compounds useful as allosteric potentiators/positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds, for example, in treating neurological and psychiatric disorders or other disease state associated with glutamate dysfunction.</p> |
申请公布号 |
CA2779298(A1) |
申请公布日期 |
2011.04.28 |
申请号 |
CA20102779298 |
申请日期 |
2010.10.22 |
申请人 |
VANDERBILT UNIVERSITY |
发明人 |
CONN, P. JEFFREY;LINDSLEY, CRAIG W.;HOPKINS, COREY R.;NISWENDER, COLLEEN M.;GOGLIOTTI, ROCCO D.;SALOVICH, JAMES M. |
分类号 |
C07D401/12;A61K31/40;A61K31/4025;A61K31/427;A61K31/433;A61K31/4439;A61K31/444;A61K31/4709;A61K31/538;A61P25/00;C07D207/48;C07D401/14;C07D403/12;C07D405/12;C07D405/14;C07D409/14;C07D413/14;C07D417/12;C07D417/14 |
主分类号 |
C07D401/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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