| 摘要 |
The present invention relates to compounds of formula (I) wherein X1 to X5, Y, Z1 to Z3, and R have the meaning as cited in the description and the claims. Said compounds are useful as JAK inhibitors for the treatment or prophylaxis of immunological, inflammatory, autoimmune, allergic disorders, and immunologically-mediated diseases. The invention also relates to pharmaceutical compositions including said compounds, the preparation of such compounds as well as the use as medicaments. |
| 申请人 |
CELLZOME LIMITED;RAMSDEN, NIGEL;HARRISON, RICHARD JOHN;OXENFORD, SALLY;BELL, KATHRYN;PITON, NELLY;DAGOSTIN, CLAUDIO;BOUSSARD, CYRILLE;RATCLIFFE, ANDREW |
发明人 |
RAMSDEN, NIGEL;HARRISON, RICHARD JOHN;OXENFORD, SALLY;BELL, KATHRYN;PITON, NELLY;DAGOSTIN, CLAUDIO;BOUSSARD, CYRILLE;RATCLIFFE, ANDREW |
