发明名称 METHOD FOR PRODUCING GENE TRANSFER AGENT
摘要 PROBLEM TO BE SOLVED: To provide a method for producing a gene transfer agent, by which the gene transfer agent narrow in molecular weight distribution and excellent in gene transfer activity can efficiently be produced by a photo-irradiation living polymerization. SOLUTION: The method for producing the gene transfer agent, including a process for performing the photo-irradiation living polymerization in a solution, is characterized by making light-reflecting particles present in the solution. By performing the photo-irradiation living polymerization in the presence of the light-reflecting particles, the light-reflecting particles can reflect irradiated light in many directions to spread the light in the whole area of the system. Thus, the photo-irradiation living polymerization can uniformly proceed in the solution to give the gene transfer agent having a narrow molecular weight distribution. COPYRIGHT: (C)2011,JPO&INPIT
申请公布号 JP2011084515(A) 申请公布日期 2011.04.28
申请号 JP20090238451 申请日期 2009.10.15
申请人 BRIDGESTONE CORP;NATIONAL CEREBRAL & CARDIOVASCULAR CENTER 发明人 NAKAYAMA YASUHIDE;NEMOTO YASUSHI
分类号 A61K48/00;A61K47/32;A61P9/00;A61P9/10;A61P31/18;A61P35/00;A61P35/04;C08F2/44;C08F2/50 主分类号 A61K48/00
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