发明名称 |
Targeted gene modification by parvoviral vectors |
摘要 |
This invention provides methods for obtaining targeted gene modification in vertebrate cells using parvoviral vectors, including adeno-associated virus (AAV). The parvoviral vectors used in the methods of the invention are capable of targeting a specific genetic modification to a preselected target locus in a cellular genome by homologous pairing.
|
申请公布号 |
US2011097804(A1) |
申请公布日期 |
2011.04.28 |
申请号 |
US20030423604 |
申请日期 |
2003.04.24 |
申请人 |
UNIVERSITY OF WASHINGTON |
发明人 |
RUSSELL DAVID W.;HIRATA ROLI K. |
分类号 |
A01K67/027;C12N15/87;C12N5/10;C12N15/09;C12N15/864 |
主分类号 |
A01K67/027 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|