发明名称 |
Chiral Stationary Phases For Chromatography Based On Aromatic Allyl Amines |
摘要 |
New chiral stationary phases (CSPs) based on chiral selectors covalently bound on a solid support were prepared. Chiral selectors were obtained from enantiomerically pure aromatic amines and 3,5-dinitrobenzoic acid and then linked to the support surface through the allylic double bond. Such obtained materials allow enantioseparation of racemates or enantiomerically enriched compounds. These chiral stationary phases can be used as fillings in chromatographic columns for enantiomer separation of naproxen type drugs and other similar non-steroidal anti-inflammatory drugs (NSAID) by means of high performance liquid chromatography on both the analytical and preparative scale.
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申请公布号 |
US2011094966(A1) |
申请公布日期 |
2011.04.28 |
申请号 |
US20100961292 |
申请日期 |
2010.12.06 |
申请人 |
VINKOVIC VLADIMIR;KONTREC DARKO;LANDEK GORAN |
发明人 |
VINKOVIC VLADIMIR;KONTREC DARKO;LANDEK GORAN |
分类号 |
C07F7/10;B01D15/38;G01N30/00 |
主分类号 |
C07F7/10 |
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