TRANSDERMALLY ABSORBABLE DONEPEZIL-CONTAINING PREPARATION

摘要

Disclosed is a transdermally absorbable donepezil-containing preparation which enables the administration of donepezil in a sustained manner for a long period and can achieve both the rapid increase in blood donepezil level and the sustained release of donepezil. The transdermally absorbable donepezil-containing preparation comprises an adhesive patch base material comprising a hydrophobic polymer and an absorption-enhancing agent and donepezil (an active ingredient) dissolved in the adhesive patch base material, wherein the absorption-enhancing agent comprises at least one component selected from lauryl alcohol, triethyl citrate, isopropyl myristate, cetyl lactate, oleyl alcohol, sorbitan monooleate, polyethylene glycol monostearate, lauromacrogol, N-methyl-2-pyrrolidone and triacetin.