发明名称 |
ANTIBODIES THAT NEUTRALIZE BOTULINUM NEUROTOXINS |
摘要 |
This disclosure provides antibodies that specifically bind to and typically neutralize botulinum neurotoxins (e.g., BoNT/A, BoNT/B, BoNT/E, etc.) and the epitopes bound by those antibodies. The antibodies and derivatives thereof and/or other antibodies that specifically bind to the neutralizing epitopes provided herein can be used to neutralize botulinum neurotoxin and are therefore also useful in the treatment of botulism. |
申请公布号 |
EP2313434(A2) |
申请公布日期 |
2011.04.27 |
申请号 |
EP20090803617 |
申请日期 |
2009.07.30 |
申请人 |
THE REGENT OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
MARKS, JAMES, D.;LOU, JIANLONG;RODRIGUEZ, MARIA CONSUELOS GARCIA;GEREN, ISIN, N. |
分类号 |
C07K16/12;A61K39/08;C12P21/08 |
主分类号 |
C07K16/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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