发明名称 |
PYRIMIDINE DERIVATIVES FOR TREATMENT OF ALZHEIMER'S DISEASE |
摘要 |
<p>The invention encompasses pyrimidine derivatives as gamma secretase modulators, useful for treating diseases associated with the deposition of beta-amyloid peptide in the brain, such as Alzheimer's disease, or of preventing or delaying the onset of dementia associated with such diseases. Pharmaceutical compositions and methods of use are included.</p> |
申请公布号 |
EP2312946(A1) |
申请公布日期 |
2011.04.27 |
申请号 |
EP20090807062 |
申请日期 |
2009.07.31 |
申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
RIVKIN, ALEXEY, A.;AHEARN, SEAN, P.;CHICHETTI, STEPHANIE, M. |
分类号 |
A61K31/505;A61K31/70;C07D401/12 |
主分类号 |
A61K31/505 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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