| 发明名称 |
QUINOLINE OR ISOQUINOLINE SUBSTITUTED P2X7 ANTAGONISTS |
| 摘要 |
The present invention is related to novel compounds of formula (I) having P2X7 antagonistic properties, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment or prophylaxis of diseases associated with P2X7 receptor activity in animals, in particular humans. (I)
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| 申请公布号 |
US2011092481(A1) |
申请公布日期 |
2011.04.21 |
| 申请号 |
US20090988891 |
申请日期 |
2009.04.21 |
| 申请人 |
JANSSEN PHARMACEUTICA NV |
发明人 |
LOVE CHRISTOPHER JOHN;LEENAERTS JOSEPH ELISABETH;COOYMANS LUDWIG PAUL;LABSACK DONALD ALEC;BRANSTETTER BRYAN JAMES;RECH JASON CHRISTOPHER;GLEASON ELIZABETH ANN;VENABLE JENNIFER DIANE;WIENER DANIELLE;SMITH DEBORAH MARGARET;BREITENBUCHER JAMES GUY |
| 分类号 |
A61K31/4709;A61K31/4725;A61K31/496;A61K31/506;A61K31/5377;A61K31/55;A61K31/553;A61P43/00;C07D401/14;C07D413/14 |
主分类号 |
A61K31/4709 |
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