发明名称 |
BACLOFEN AND R-BACLOFEN GASTRORETENTIVE DRUG DELIVERY SYSTEMS |
摘要 |
A biodegradable, multi-layered controlled release gastroretentive baclofen or R-baclofen dosage form which is optionally divided into a first dosage of baclofen or R-baclofen for immediate release and a second dosage of baclofen or R-baclofen for controlled release in the stomach and gastrointestinal tract of a patient, folded into a capsule which disintegrates upon contact with gastric juice and the dosage form unfolds rapidly upon contact with gastric juice. The biodegradable, multi-layered gastroretentive dosage forms of the invention provide fast onset of baclofen or R-baclofen activity with prolonged absorption and minimal undesirable side effects. |
申请公布号 |
US2011091542(A1) |
申请公布日期 |
2011.04.21 |
申请号 |
US20100797441 |
申请日期 |
2010.06.09 |
申请人 |
INTEC PHARMA LTD. |
发明人 |
NAVON NADAV;SHVETZ JULIA;MOOR EYTAN;KIRMAYER DAVID;KLUEV ELENA;MASRI SHUHER;CARNI GIORA;WEISS ZEEV |
分类号 |
A61K9/54;A61K9/00;A61K9/52;A61K31/195;A61P1/00;A61P7/00;A61P25/00;A61P25/06;A61P25/24;A61P25/30;A61P25/32;A61P29/00 |
主分类号 |
A61K9/54 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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