Monomeric and dimeric trioxane fluoroaryl amides, 5-carbon-linked, C-10 non-acetal trioxane dimer esters; trioxane silylamides; and trioxane dimer orthoesters and methods of their use for treating subjects infected with malaria or other parasitic infectious diseases including, but not limited to, toxoplasmic infection; subjects afflicted with psychiatric conditions associated with toxoplasmic infection; and subjects afflicted with cancer.
申请公布号
WO2010135427(A3)
申请公布日期
2011.04.21
申请号
WO2010US35404
申请日期
2010.05.19
申请人
THE JOHNS HOPKINS UNIVERSITY;POSNER, GARY, H.;WOODARD, LAUREN, E.;LEVINE, DAVID, R.;MOON, DEUK KYU;MOTT, BRYAN, T.