CONTROLLED RELEASE PALIPERIDONE COMPOSITION

摘要

The present invention relates to A controlled-release pharmaceutical tablet, comprising: (a) an inner hydrogel tablet core comprising paliperidone or a pharmaceutically acceptable salt thereof and a pH-independently gelling polymer; and (b) an outer hydrogel layer surrounding said inner tablet core comprising a pH-independently gelling polymer; wherein said outer layer does not contain paliperidone or a pharmaceutically acceptable salt thereof, to a method of making such tablets and for use in medicine.