| 发明名称 |
COMPOUNDS AND USES THEREOF IN MODULATING AMYLOID BETA |
| 摘要 |
PROBLEM TO BE SOLVED: To provide a compound having activity to modulate an amyloid beta (Aβ) level, and a method of producing the compound. SOLUTION: The compound is expressed by formula (I) and also by the formula specifying A and B (wherein one or two of G is N, and G of the remainders are each CH; each E is independently CR<SP>1</SP>; and X is a halogen). The compound is useful for treatment of diseases associated with an aberrant Aβ level and/or optionl conditions in which modulation of an Aβ level gives therapeutic effects. COPYRIGHT: (C)2011,JPO&INPIT
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| 申请公布号 |
JP2011079852(A) |
申请公布日期 |
2011.04.21 |
| 申请号 |
JP20100268183 |
申请日期 |
2010.12.01 |
| 申请人 |
NEUROGENETIC PHARMACEUTICALS INC |
发明人 |
CHENG SOAN;COMER DANIEL D;MAO LONG;BALOW GUITY P;PLEYNET DAVID |
| 分类号 |
C07D233/60;A61K;A61K31/40;A61K31/4164;A61K31/425;A61K31/4439;A61K31/497;A61K31/50;A61K31/505;A61K31/53;A61K31/535;A61P25/14;A61P25/16;A61P25/28;C07D233/68;C07D277/04;C07D277/42;C07D401/04;C07D413/00;C07D417/04;C07D417/10;C07D417/12;C07D417/14 |
主分类号 |
C07D233/60 |
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