发明名称 RECEPTOR TYPE KINASE MODULATORS AND METHODS OF USE
摘要 <P>PROBLEM TO BE SOLVED: To provide a compound having receptor kinase activity especially one for modulating ephrin and EGFR, and a method of treating the receptor kinase activity-mediated disorder utilizing the compound and drug composition. <P>SOLUTION: This is a compound represented by chemical formula (I). The receptor kinase activity-mediated disorder includes, for example, cell growth of an abnormal level (that is tumor growth), programmed cell death (apotosis), migration and invasion of a cell and disorders having vascular formation relating to tumor growth as a part of characteristics. <P>COPYRIGHT: (C)2011,JPO&INPIT
申请公布号 JP2011079844(A) 申请公布日期 2011.04.21
申请号 JP20100259281 申请日期 2010.11.19
申请人 SYMPHONY EVOLUTION INC 发明人 RICE KENNETH D;ANAND NEEL KUMAR;BUSSENIUS JOERG;COSTANZA SIMONA;KENNEDY ABIGAIL R;KIM ANGIE I;PETO CSABA J;TSANG TSZE H;BLAZEY CHARLES M
分类号 C07D239/94;A61K31/505;A61K31/506;A61K31/5377;A61K31/5383;A61K31/553;A61K31/7064;A61P1/04;A61P9/00;A61P9/10;A61P17/06;A61P19/02;A61P25/00;A61P27/02;A61P29/00;A61P35/00;A61P37/06;A61P43/00;C07D401/12;C07D403/12;C07D405/12;C07D409/12;C07D413/12;C07D413/14;C07D417/12;C07D417/14;C07D451/04;C07D451/06;C07D471/04;C07D487/04;C07D493/04;C07D493/20;C07D495/04;C07D498/04;C07D513/04;C07H17/02 主分类号 C07D239/94
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