发明名称 |
INDUCTION OF PLURIPOTENT CELLS |
摘要 |
The slow kinetics and low efficiency of reprogramming methods to generate human induced pluripotent stem cells (iPSCs) impose major limitations on their utility in biomedical applications. Here we describe a chemical approach that dramatically improves (>200 fold) the efficiency of iPSC generation from human fibroblasts, within seven days of treatment. This will provide a basis for developing safer, more efficient, non-viral methods for reprogramming human somatic cells. |
申请公布号 |
WO2011047300(A1) |
申请公布日期 |
2011.04.21 |
申请号 |
WO2010US52896 |
申请日期 |
2010.10.15 |
申请人 |
THE SCRIPPS RESEARCH INSTITUTE;LIN, TONGXIANG;DING, SHENG |
发明人 |
LIN, TONGXIANG;DING, SHENG |
分类号 |
C12N5/00 |
主分类号 |
C12N5/00 |
代理机构 |
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代理人 |
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地址 |
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