发明名称 High affinity antibody antagonists of interleukin-13 receptor alpha 1
摘要 High affinity antibody antagonists of human interleukin-13 receptor alpha 1 are disclosed. The antibody molecules are effective in the inhibition of IL-13R±1-mediated activities and, accordingly, present desirable antagonists for the use in the treatment of conditions associated with hIL-13R±1 activity. The present disclosure also provides nucleic acid encoding said antibody molecules, vectors, host cells, and compositions comprising the antibody molecules. Methods of using the antibody molecules for inhibiting or antagonizing IL-13R±1-mediated activities are also disclosed.
申请公布号 AU2011201507(A1) 申请公布日期 2011.04.21
申请号 AU20110201507 申请日期 2011.04.04
申请人 CSL LIMITED 发明人 ANDREW DONALD NASH;MANUEL BACA;LOUIS JERRY FABRI;DENNIS ZALLER;WILLIAM R. STROHL;ZHIQIANG AN
分类号 C07K16/18;A61K39/395;A61P43/00;C12N15/00;C12N15/11 主分类号 C07K16/18
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