发明名称 THERAPEUTIC USE OF QUINONOID DERIVATIVES OF CANNABINOIDS
摘要 The present invention relates to cannabinoic quinone compounds, and especially to their medical use. In particular five cannabinoic quinones, designated HU-331, HU-336, HU-345, HU-395 and HU-396 are herein described as active agents in pharmaceutical compositions. Said compounds and compositions thereof are intended for the treatment of inflammatory, infectious, auto-immune and particularly hyperproliferative disorders. Thus, the compounds of the invention may be used as anti-tumor agents, or for the treatment of cancer. Furthermore, three of these compounds, HU-345, HU-395 and HU-396, are novel cannabinoic quinones and thus are also claimed herein.
申请公布号 US2011092584(A1) 申请公布日期 2011.04.21
申请号 US20090597166 申请日期 2009.11.16
申请人 YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREWUNIVERSITY OF JERUSALEM 发明人 MECHOULAM RAPHAEL;KOGAN NATALYA M.;RABINOWITZ RUTH;SCHLESINGER MICHAEL
分类号 A61K31/122;A61K31/352;A61P17/06;A61P29/00;A61P31/00;A61P35/00;A61P37/00;C07C49/603;C07C50/30;C07D311/80 主分类号 A61K31/122
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