发明名称 ENZYMATIC PROCESS FOR OBTAINING 17 ALPHA- MONOESTERS OF CORTEXOLONE AND/OR ITS 9,11- DEHYDRODERIVATIVES
摘要 The present invention refers to a new enzymatic process for obtaining 17α-monoesters of cortexolone and/or its 9,11-dehydroderivatives starting from the corresponding 17α,21-diesters which comprises an enzymatic alcoholysis reaction. Furthermore, the present invention refers to new crystalline forms of cortexolone 17α-propionate and 9,11-dehydro-cortexolone 17α-butanoate.
申请公布号 US2011092472(A1) 申请公布日期 2011.04.21
申请号 US20080671932 申请日期 2008.07.24
申请人 COSMO SPA 发明人 AJANI MAURO;MORO LUIGI
分类号 A61K31/573;A61P15/00;A61P15/16;A61P17/00;A61P17/08;A61P17/10;A61P17/14;A61P35/00;C07J5/00;C12P33/00 主分类号 A61K31/573
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