| 发明名称 |
NOVEL N-SUBSTITUTED-PYRROLIDINES AS INHIBITORS OF MDM2-P-53 INTERACTIONS |
| 摘要 |
There are provided compounds of the formula (I) wherein X, Y, R1, R2, R3, R3, R4, and R5 are as described herein and enantiomers and pharmaceutically acceptable salts and esters thereof which are useful as anticancer agents.
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| 申请公布号 |
CA2774512(A1) |
申请公布日期 |
2011.04.21 |
| 申请号 |
CA20102774512 |
申请日期 |
2010.10.11 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
BARTKOVITZ, DAVID JOSEPH;CHU, XIN-JIE;LIU, JIN-JUN;ROSS, TINA MORGAN;ZHANG, ZHUMING |
| 分类号 |
C07D207/16;A61K31/402;A61K31/4025;A61P35/00;C07D401/06;C07D401/12;C07D403/12 |
主分类号 |
C07D207/16 |
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