PROCESS FOR ADENOVIRUS PURIFICATION FROM HIGH CELL DENSITY CULTURES
摘要
The invention provides methods for large-scale adenovirus purification from high cell density suspensions, using host cell DNA fragmentation and/or precipitation followed by a clarification step with tangential flow filtration.
申请公布号
WO2011045381(A1)
申请公布日期
2011.04.21
申请号
WO2010EP65436
申请日期
2010.10.14
申请人
CRUCELL HOLLAND B.V.;DE VOCHT, MARCEL, LEO;VEENSTRA, MARLOES