发明名称 DUAL-ACTING IMIDAZOLE ANTIHYPERTENSIVE AGENTS
摘要 The invention is directed to compounds having the formula: wherein: Ar, r, R2-3, X, and R5-7 are as defined in the specification, and pharmaceutically acceptable salts thereof. These compounds have AT1 receptor antagonist activity and neprilysin inhibition activity. The invention is also directed to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.
申请公布号 US2011092551(A1) 申请公布日期 2011.04.21
申请号 US20100974210 申请日期 2010.12.21
申请人 THERAVANCE, INC. 发明人 ALLEGRETTI PAUL;CHOI SEOK-KI;GENDRON ROLAND;FATHEREE PAUL R.;JENDZA KEITH;MCKINNELL ROBERT MURRAY;MCMURTRIE DARREN;OLSON BROOKE
分类号 A61K31/4196;A61K31/41;A61K31/415;A61K31/4164;A61K31/4412;A61P9/12;C07D211/76;C07D231/12;C07D233/64;C07D249/08;C07D257/04;G01N33/53 主分类号 A61K31/4196
代理机构 代理人
主权项
地址
您可能感兴趣的专利