发明名称 |
METHODS AND COMPOSITIONS FOR THE DELIVERY OF VACCINES TO DISRUPTED EPITHELIUM |
摘要 |
The invention features immunogenic compositions and methods useful for eliciting an immune response. In preferred embodiments, papillomavirus or adenovirus vectors are used to elicit exceptionally potent antibody and T cells responses in disrupted epithelium. The methods are useful in preventing or treating a subject having a disease or an infection. In particular examples, the methods are useful for preventing or treating a viral infection.
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申请公布号 |
US2011091496(A1) |
申请公布日期 |
2011.04.21 |
申请号 |
US20090863572 |
申请日期 |
2009.01.21 |
申请人 |
GRAHAM BARNEY S;BUCK CHRISTOPHER B;ROBERTS JEFFREY N;JOHNSON TERESA R;NICEWONGER JOHN;KINES RHONDA;SCHILLER JOHN T |
发明人 |
GRAHAM BARNEY S.;BUCK CHRISTOPHER B.;ROBERTS JEFFREY N.;JOHNSON TERESA R.;NICEWONGER JOHN;KINES RHONDA;SCHILLER JOHN T. |
分类号 |
A61K39/12;A61K39/00;A61K39/155;A61K39/21;A61K39/235;A61P31/12;A61P37/00;C07H21/00;C12N15/63 |
主分类号 |
A61K39/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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