发明名称 |
TREATMENT OF SUICIDAL IDEATION OR BEHAVIOR USING INHIBITORS OF NICOTINIC ACETYLCHOLINE RECEPTORS |
摘要 |
The invention concerns methods of treating suicidal ideation or behavior in a subject in need thereof, comprising decreasing endogenous nicotinic acetylcholine receptor (nAChR) activity in the subject; therapeutic packages for treating suicidal ideation or behavior; and methods for determining the efficacy of a treatment for suicidal ideation or behavior. In some embodiments, the treatment methods comprise administering to the subject an effective amount of an inhibitor of a nAChR, such as a lithium compound, mecamylamine, clozapine, or asenapine. |
申请公布号 |
WO2011047341(A2) |
申请公布日期 |
2011.04.21 |
申请号 |
WO2010US52949 |
申请日期 |
2010.10.15 |
申请人 |
UNIVERSITY OF SOUTH FLORIDA;SHEEHAN, DAVID, V.;SHYTLE, R., DOUGLAS |
发明人 |
SHEEHAN, DAVID, V.;SHYTLE, R., DOUGLAS |
分类号 |
A61K31/407;A61K31/55;A61K33/14;A61P25/18;A61P25/24 |
主分类号 |
A61K31/407 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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