发明名称 |
COMPOSITIONS AND METHODS FOR THE PRODUCTION OF ALPHA-HERPESVIRUS 2 |
摘要 |
The present invention relates to virus growth media that improve the yield of alpha-herpesviruses (e.g., HSV-2) grown in cell cultures. The growth media of the invention include two additives, a disaccharide and a lipid mixture, that can be added to serum-free or serum-enriched growth media to improve the efficiency of virus production. The invention further provides methods of producing alpha-herpesviruses (e.g., HSV-2) in such growth media. |
申请公布号 |
EP2310495(A1) |
申请公布日期 |
2011.04.20 |
申请号 |
EP20090807164 |
申请日期 |
2009.08.11 |
申请人 |
SANOFI PASTEUR BIOLOGICS CO. |
发明人 |
DELAGRAVE, SIMON;OUBELAID, RACHID;HAMBERGER, JOHN |
分类号 |
C12N7/00;C12N5/00;C12N7/01;C12N7/02 |
主分类号 |
C12N7/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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