摘要 |
The invention relates to optoelectronic systems for detecting one or more target particles, for example bacteria and antigens. The system includes a reaction chamber, a specimen collector, an optical detector, and a reservoir containing cells, each of the cells having receptors which are present on the surface of each cell and are specific for the target particle to be detected, where binding of the target particle to the receptors directly or indirectly activates a reporter molecule, for example aequorin or indo-1, thereby producing a measurable optical signal. |
申请人 |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY |
发明人 |
HARPER, JAMES DOUGLAS;MATHEWS, RICHARD HART;JOHNSON, BERNADETTE;PETROVICK, MARTHA SUSAN;RUNDELL, ANN;NARGI, FRANCES ELLEN;STEPHENS, TIMOTHY;MENDENHALL, LINDA MARIE;HOLLIS, MARK ALEXANDER;YOUNG, ALBERT M.;RIDER, TODD HARRISON;SCHWOEBEL, ERIC DAVID;VIAN, TRINA RAE |