发明名称 |
FIBROBLAST GROWTH FACTOR RECEPTOR-1 INHIBITORS AND METHODS OF TREATMENT THEREOF |
摘要 |
<p>The present invention relates to an antibody, or fragment thereof that is specific for fibroblast growth factor receptor (FGFR)-1(IIIb), FGFR-1(IIIc), and/or FGFR-4(IIIc). The present invention further provides methods of antagonizing and neutralizing FGFR-1 and/or FGFR-4 as a treatment for obesity, diabetes, and/or a condition related thereto, including reducing food intake or total body mass.</p> |
申请公布号 |
EP1680140(B1) |
申请公布日期 |
2011.04.20 |
申请号 |
EP20040796034 |
申请日期 |
2004.10.18 |
申请人 |
IMCLONE LLC |
发明人 |
SUN, HAIJUN;SHEN, JUQUN;TONRA, JAMES, R. |
分类号 |
A61K39/395;A61K;A61K31/519;A61P3/04;A61P3/10;A61P9/00;C07K16/28;C12N15/10;C12N15/13 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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