FLUORESCENCE QUENCHER MOLECULES AS WELL AS METHODS AND USES INVOLVING THE SAME

摘要

The present invention relates to novel pyridinyl-isoquinoline-dione derivatives, methods of producing of these derivatives, conjugates comprising the novel pyridinyl-isoquinoline dione derivatives and (i) a solid support, or (ii) a biomolecule, methods of producing of these conjugates as well as the use of these conjugates as quenchers in fluorescence resonance energy transfer (FRET).