发明名称 |
Labeling targeting agents with gallium-68 and gallium-67 |
摘要 |
A method and compositions are described for labeling a targeting agent with Ga-68, in which eluate from an acid-eluted Ge-68/Ga-68 generator is combined with a macrocycle-containing targetable agent. The labeling method and compositions disclosed ensure that a simple elution of gallium-68, taken directly from a generator, can be used without further manipulation to quantitatively label a macrocycle-containing targetable agent. The Ga-68 labeled targeting agent so produced is useful with specific targeting agents, and is most especially useful in a pretargeting method for positron emission tomographic detection. |
申请公布号 |
EP2311500(A1) |
申请公布日期 |
2011.04.20 |
申请号 |
EP20100011207 |
申请日期 |
2002.12.23 |
申请人 |
IMMUNOMEDICS, INC. |
发明人 |
GRIFFITHS, GARY, L.;MCBRIDE, WILLIAM, J. |
分类号 |
A61K51/00;A61K51/08;A61K31/00;A61K47/48;A61K51/10;A61M36/14;C07K14/00 |
主分类号 |
A61K51/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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