| 摘要 |
The present invention refers to a pharmaceutical composition that comprises the combination of an active principle (a) for reducing the intestinal absorption of glucose and hepatic gluconeogenesis; an active principle (b) for inhibiting the uptake of serotonin of the family 5HT, dopamine and noradrenalin; and a third active principle (c) for increasing the insulin action over the peripheral tissues along with one or more acceptable pharmaceutical excipients. Where (a) is metformin, (b) is sibutramin and (c) a chromium source. Aid composition is used for treating overweight, obesity, diabetes mellitus type II, hyperlipidemia, dyslipidemia, arterosclerosis and metabolic syndrome, metabolic disorders and the complications thereof in mammals, specially humans.
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